In connection with 1, 1-diethyl-2-methyl-3-diphenylmethylenepyrrolidinium bromide (1) (anticholinergic agent), 1, 1, 4-trimethyl-(2) and 1, 1, 5-trimethyl-3-diphenylmethylene-pyrrolidinium iodide (3) were synthesized. In the pharmacological examination of anticholinergic activity, the relative potencies of 2 and 3 were 0.01 and 0.27 respectively, in contrast to atropine which was defined as 1.00.
