threo-1-Hydroxy-2-(isopropylamino)-[10]-paracyclophane (1) was prepared and resolved into one enantiomer. The absolute configuration of 1 was deduced from the analysis of circular dichroism (CD) spectra using Snatzke's sector rule and induced CD of Cu(su)2(ip)2 and Pr(DPM)3. Intrinsic sympathomimetic activity of 1 and threo-and erythro-1-(4-tolyl)-2-isopropylamino-1-propanol were tested on the isolated guinea pig heart.
