抄録
Hydrazine formation took place in man after the oral administration of isoniazid. The excreted amount of free hydrazine in human urine was determined quantitatively by the new method, i.e. mass fragmentography using 15N-hydrazine as an internal standard. The unchanged isoniazid and the other metabolites, acetylisoniazid, monoacetylhydrazine and diacetylhydrazine were simultaneously analyzed.
