Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Origin of Plasma Uric Acid induced by l-Epinephrine
米谷 行男石井 光雄山田 加寿子小川 保直
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キーワード: rat
ジャーナル フリー

1977 年 25 巻 3 号 p. 457-463

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抄録
The origin of increased plasma uric acid in l-epinephrine-induced hyperuricemia was studied. It was shown that uric acid is increased by an extra-hepatic process, in particular by reduction in the intestinal adenosine-tri-phosphate level. Further, from evidence for the existence of plasma xanthine oxidase, it was shown that production of uric acid by an extra-hepatic process is very likely in many mammals, even in man.
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© The Pharmaceutical Society of Japan
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