抄録
The radioimmunoassay for methamphetamine (I) in urine of man has been established by use of the 125I-labelled derivative of N-[3-(p-hydroxyphenylacetylamino) propyl]-methamphetamine (V) in sensitivity of 8.0 ng/100μl. The antigen binding capacity of the antiserum prepared form N-carboxymethylmethamphetamine-BSA (II) was determined by a new method of immunoassay using fluorescence labelled N-(3-dansylaminopropyl) methamphetamine (IV) ("fluoroimmunoassay"). The specificity of the antibody was examined by its cross reaction with several methamphetamine analogues.