Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Reaction of Biguanides and Related Compounds. XIV. Cyclization of Amidinothioureas with Some Carbonyl Compounds
古川 潮大川原 正野口 芳秀宮崎 隆一
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キーワード: cyclization
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1978 年 26 巻 1 号 p. 314-317

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The reaction of amidinothioureas (II) with aldehydes or acetone and with methyl chloroacetate were found to form 6-amino-4-mercapto-2-substituted 1, 2-dihydro-1, 3, 5-triazines (III) and 2-guanidylidene-4-thiazolidones (V), respectively.

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© The Pharmaceutical Society of Japan
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