Preparation of Some Ring-Oxygenated Phenacyl Bromides

Abstract

3, 4-Dimethoxy, 3-benzyloxy-4-methoxy, 3, 4, 5-trimethoxy, 2-hydroxy-3, 4-dimethoxy, and 2-benzyloxy-3, 4-dimethoxy derivatives (3a-e) of phenacyl bromide have been prepared in 44-84% yields from the corresponding acetophenones by bromination with bromine in a mixture of ether and chloroform.