Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Oxidative Cyclization of 6-Substituted Amino-5-benzylideneamino-1, 3-dimethyluracils to 9-Substituted 8-Aryltheophyllines with Thionyl Chloride
KEITARO SENGA, YUKAKO KANAMORI, SADAO NISHIGAKI
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Keywords: 8-aryl-9-phenyltheophyllines
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1978 Volume 26 Issue 10 Pages 3240-3241

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Abstract

Treatment of 6-substituted amino-5-benzylideneamino-1, 3-dimethyluracils with thionyl chloride at 0° for 30 min gave the corresponding 9-substituted 8-aryltheophyllines in 56-98% yields.

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© The Pharmaceutical Society of Japan
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