Synthesis of 2, 3, 17 β-Trihydroxyestra-1, 3, 5 (10)-trien-6-one and Its Related Compounds

Abstract

2, 3, 17 β-Trihydroxyestra-1, 3, 5 (10)-trien-6-one (7) and its methylated derivatives (6, 12, and 16) have been prepared for the biological investigation. The preparation method and the results of the instrumental analyses including nuclear magnetic resonance and ultraviolet spectra of these materials are described.