Studies on Azole Compounds. V. Reaction of 4-Phenyloxazole 3-Oxides with Arylisocyanates to give Imidazolino [4, 5-d]-oxazolid-2-one Derivatives

抄録

Reaction of 4-phenyloxazole 3-oxides (III) with arylisocyanates afforded imidazolin-[4, 5-d] oxazolid-2-one derivatives (Vaa-Vbc). On pyrolysis of Vaa, Vab and Vba, a rearrangement of methyl group on the 5-position of imidazoline ring to yield imidazolinones (VIaa, VIab and VIba) was observed. When imidazolinones were treated with large excess of NaBH₄, reduction of ring amide group occurred.