Application of INDOR and NOE Techniques to Determination of the Substitution Pattern on an Aromatic Ring of Erythrinan Alkaloids

Abstract

The utility of the INDOR and NOE techniques for the determination of the substitution pattern on the aromatic ring of erythrinan alkaloids is demonstrated. Synthesis of 3α, 16-dimethoxyerythrinan-1 (6)-ene (III) was accomplished by a route similar to that developed by Mondon, et al.