The Constituents of Schizandra chinensis BAILL. V. The Structures of Four New Lignans, Gomisin N, Gomisin O, Epigomisin O and Gomisin E, and Transformation of Gomisin N to Deangeloylgomisin B

Abstract

Four new dibenzocyclooctadiene lignans, gomisins N (1), O (2) and E (4), and epigomisin O (3), together with a known lignan (+)-deoxyschizandrin (5) were isolated from the fruits of Schizandra chinensis BAILL. (Schizandraceae). The structures of the new lignans were elucidated by chemical and spectral studies. The transformation of 1 to deangeloylgomisin B (debenzoylgomisin C) (6) is also described.