Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Fractional Analysis of Zinc in Rabbit Plasma
KAZUICHI HAYAKAWATOSHIO IMANARISHUKO ASAZUMARYOICHI KIZUMOTOICHI MIYAZAKI
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Keywords: fasting
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1979 Volume 27 Issue 11 Pages 2849-2851

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Abstract

An effective method for fractional analysis of zinc in rabbit plasma was established, using polyethylene glycol. Rabbit plasma zinc was separated into two fractions ; the zinc profile in the precipitate showed two peaks, which were not albumin-bound zinc, on gel filtration, while the zinc in the supernatant proved to be albumin-bound zinc. The proposed method was used to investigate the effect of feeding on plasma zinc in rabbits. The decrease of total plasma zinc on feeding was significant, and was mainly due to that of albumin-bound zinc.

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© The Pharmaceutical Society of Japan
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