Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Structure of Manevalic and Azizic Acids, Two New Triterpenes from Cornulaca monacantha DEL.
ABDELAZIZ DAWIDARJOHANNES REISCHMANIVAL AMER
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1979 Volume 27 Issue 12 Pages 2938-2942

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Abstract
Two new triterpene acids were isolated from the plant Cornulaca monacantha DEL. The first acid was assigned the structure 3β, 6α-dihydroxyolean-12-en-27-oic acid I and was given the trivial name manevalic acid. The other compound was assigned the structure 3β, 6α-dihydroxyolean-12-en-27, 28-dioic acid II and named azizic acid. These assignments were based on spectral and chemical studies. The chemical correlation between manevalic acid and the known triterpene astilbic acid, 3β, 6β-dihydroxyolean-12-en-27-oic acid, was established through oxidation of their methyl esters to methyl 3, 6-dioxoolean-12-en-27-oate IC.
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© The Pharmaceutical Society of Japan
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