Author's Organization：Faculty of Pharmaceutical Sciences, University of Tokyo Faculty of Pharmaceutical Sciences, University of Tokyo Faculty of Pharmaceutical Sciences, University of Tokyo Faculty of Pharmaceutical Sciences, University of Tokyo
Condeinone (1) was oxidized to codeinone 7, 8-oxide (2) by hydrogen peroxide. Stereospecific reduction of 2 by sodium borohydride afforded codeine 7, 8-oxide (3). The configuration of 3 was confirmed by X-ray analysis.
