Abstract
The reaction of 5-hydroxy-2-phenyltetrahydro-2H-1, 2-oxazin-3-one derivatives (2) with thionyl chloride in the presence of pyridine afforded a mixture of stereoisomers of bis (3-oxo-2-phenyltetrahydro-2H-1, 2-oxazine-5-yl) sulfite derivatives (3) in total yields of 75-83%. On high-performance liquid chromatography, two meso-diastereoisomers (3-I and 3-II) and a racemic compound (3-III) were isolated.
