Stereospecific Synthesis of cis- and trans-2, 3-Epoxycycloheptanol

抄録

cis- and trans-2, 3-Epoxycycloheptanols were prepared stereospecifically from cyclohept-2-en-1-ol (1). Oxidation of 1 with tert-butyl hydroperoxide in the presence of a molybdenum catalyst gave the cis isomer (2) in high yield. The trans isomer (3) was obtained via the bromohydrin (4). The structure of 4 is discussed.