Studies on the Syntheses of Condensed Indole-4, 7-diones. II. Synthesis of Pyrrolo [1, 2-a] indole-5, 8-dione Derivatives

Abstract

Methyl 1, 2-dihydro-3H-pyrrolo [1, 2-a] benzo [f] indole-5, 10-dione-11-carboxylate (9) was synthesized starting from 2, 3-dichloronaphthoquinone (2) through a five-step procedure including a novel cyclization reaction to methyl 1-acetyl-1, 2, 3, 4-tetrahydro-6H-naphtho-[2, 3-b] azocine-5, 7, 12-trione-6-carboxylate (13).