1981 Volume 29 Issue 4 Pages 1156-1159
Reaction of silyl enol ethers of ketones and aldehydes with 1, 3, 5-trialkylhexahydro-1, 3, 5-triazines in the presence of acetyl chloride and titanium tetrachloride afforded α-N-alkylacetamidomethylated carbonyl compounds. Thus, the reaction provides a convenient, general method for introduction of the N-alkylacetamidomethyl moiety at a position α to a carbonyl group.