Stichlorogenol and Dehydrostichlorogenol, Genuine Aglycones of Stichlorosides A₁, B₁, C₁ and A₂, B₂, C₂, from the Sea Cucumber Stichopus Chloronotus (BRANDT)

Abstract

Six new antifungal triterpene-oligoglycosides named stichlorosides A₁, A₂, B₁, B₂, C₁, and C₂ have been isolated from the sea cucumber Stichopus chloronotus (BRANDT). The structures of their genuine aglycones stichlorogenol (1) (for A₁, B₁, and C₁) and dehydrostichlorogenol (2) (for A₂, B₂, and C₂) have been elucidated on the bases of chemical and physicochemical evidence together with the X-ray analysis of 1. They are the first examples of lanost-7-ene type aglycones isolated from sea cucumber.