Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Anti-Platelet Aggregation Principles from the Bark of Fraxinus japonica BLUME
小平 治良石川 正幸菰田 泰夫中嶋 暉躬
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キーワード: dopamine metabolites
ジャーナル フリー

1981 年 29 巻 8 号 p. 2391-2393

詳細
抄録
The methanol extract of the bark of Fraxinus japonica BLUME was fractionated with the guidance of inhibitory activity on rabbit platelet aggregation induced by arachidonic acid. The following active principles were identified : 3-methoxy-4-hydroxyphenylethanol (I) (which also exists in the animal body as a dopamine metabolite), p-hydroxyphenylethanol (II), 2, 6-dimethoxy-p-benzoquinone (III), compounds (IV), (V), and esculetin.
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© The Pharmaceutical Society of Japan
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