Uracil Derivatives. III. Syntheses and Growth-inhibitory Activity against L-1210 Cells of 5, 6-Disubstituted Uracils

抄録

5-(4-Halophenylthiomethyl)-6-alkoxycarbonyluracils (IIa-i) and 5-(4-halophenylthiomethyl)-6-alkylcarbamoyluracils (IVa-p) were prepared from 5-(4-halophenylthiomethyl)-6-ethoxycarbonyluracils (Ia-c). The compounds thus prepared were examined for growth inhibition of L-1210 cells in vitro.