Marine Natural Products. X. Pharmacologically Active Glycolipids from the Okinawan Marine Sponge Phyllospongia foliascens (PALLAS)

Abstract

By monitoring pharmacological activities, an anti-inflammatory active galactolipid [designated as M-5 (2)] and a sulfonoglycolipid [designated as M-6 (4)] which shows resistant activity against a complement fixation reaction have been isolated from the Okinawan marine sponge Phyllospongia foliascens (PALLAS). The structures of these pharmacologically active principles have been elucidated as 2 and 4, respectively, on the basis of chemical and physicochemical evidence.