DETHIO-TETRA (METHYLTHIO) CHETOMIN, A NEW ANTIMICROBIAL METABOLITE OF CHAETOMIUM GLOBOSUM KINZE EX FR. STRUCTURE AND PARTIAL SYNTHESIS FROM CHETOMIN

Tohru Kikuchi; Shigetoshi Kadota; Keiko Nakamura; Arasuke Nishi; Tooru Taga; Taneno Kaji; Kenji Osaki; Keisuke Tubaki

doi:10.1248/cpb.30.3846

Tohru Kikuchi, Shigetoshi Kadota, Keiko Nakamura, Arasuke Nishi, Tooru Taga, Taneno Kaji, Kenji Osaki, Keisuke Tubaki

Author information

Tohru Kikuchi
Shigetoshi Kadota
Keiko Nakamura
Arasuke Nishi
Tooru Taga
Taneno Kaji
Kenji Osaki
Keisuke Tubaki
Author's Organization：
Research Institute for Wakan-Yaku (Oriental Medicines), Toyama Medical and Pharmaceutical University
Research Institute for Wakan-Yaku (Oriental Medicines), Toyama Medical and Pharmaceutical University
Research Institute for Wakan-Yaku (Oriental Medicines), Toyama Medical and Pharmaceutical University
Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University
Japan Faculty of Pharmaceutical Sciences, Kyoto University
Faculty of Pharmaceutical Sciences, Kyoto University
Faculty of Pharmaceutical Sciences, Kyoto University
Institute of Biological Sciences, The University of Tsukuba

Keywords: X-ray analysis

JOURNAL FREE ACCESS

1982 Volume 30 Issue 10 Pages 3846-3848

DOI https://doi.org/10.1248/cpb.30.3846

Details

Abstract

Dethio-tetra (methylthio) chetomin, a new antimicrobial metabolite, was isolated from a fungus, Chaetomium globosum KINZE ex FR., and its structure was determined to be 2 on the basis of chemical correlation with chetomin and X-ray crystallographic analysis.

Corresponding author

Register with J-STAGE for free!