STEREOSELECTIVE SYNTHESIS OF (±)-SEMBURIN AND (±)-ISOSEMBURIN USING A COMMON BICYCLIC PRECURSOR

Abstract

Using the common bicyclic compound 1-oxabicyclo [3. 2. 1] octan-2-one (1), two isomeric monoterpenes, semburin (6) and isosemburin (7) isolated from Swertia japonica Makino, have been synthesized stereoselectively in racemic forms.