Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Studies on UV-labelling Agents. I. Stability of N, N-Dimethyl-4-diazomethyl Benzenesulfonamide
HISAYUKI TANIZAWAMICHIKO(SHIOKAWA) SHIRATAKIYOSHIO TAKINO
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JOURNAL FREE ACCESS

1982 Volume 30 Issue 3 Pages 1051-1053

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Abstract
The stability of the diazoalkane N, N-dimethyl-4-diazomethyl benzenesulfonamide (DDBS), used as a UV-labelling agent, was investigated. The decomposition of DDBS in solvent depended mainly on the temperature and slightly on light and moisture. Thus, the decomposition in a benzene solution kept in a refrigerator and shielded from light and moisture was very slight. DDBS in solid form stored in container shielded from light was hardly decomposed in 30 weeks. DDBS has excellent stability compared with other UV-labelling agents for acidic substances.
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© The Pharmaceutical Society of Japan
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