Abstract
In order to provide useful key intermediates for syntheses of complex oligosaccharides, anomeric 1, 2', 3', 4', 6, 6'-hexa-O-acetyl-N-acetyllactosamines (8 : α, and 9 : β) and the corresponding 3-O-benzyl ethers (5 : α, and 6 : β) were synthesized. Condensation of 1, 6-anhydro-3-O-benzyl-β-N-acetylglucosamine with acetobromogalactose by a conventional Koenigs-Knorr procedure, followed by selective acetolysis of the 1, 6-anhydro-β-linkage, provided 5 and 6. Debenzylation of 5 and 6 gave 8 and 9, respectively.
