Studies on Conjugated Nitriles. V. Reaction of 3-Benzoyl-and 3-Ethoxycarbonylacrylonitriles with Enamines

抄録

The reactions of 3-benzoylacrylonitrile (1a) with 3-amino-5, 5-dimethyl-2-cyclohexenone (2) and ethyl 3-aminocrotonate (4) gave the corresponding pyridine derivatives, 3 and 5, respectively. 3-Ethoxycarbonylacrylonitrile (1b) also reacted with ethyl 3-benzylaminocrotonate (6) and 1-ethoxycarbonylmethylene-1, 2, 3, 4-tetrahydroisoquinoline (9) to give the pyrrolin-5-one derivatives, 7 and 10, respectively.