Renal Effect of Aqueous Extract from Salviae miltiorrhizae Radix in Normal Rats

Abstract

The renal effect of Salviae miltiorrhizae Radix extract was examined in normal rats. A single intraperitoneal administration of the extract led to appreciable increments of urine volume, and urinary excretion of urea and creatinine. The extract also induced natriuretic, kaliuretic, and phosphaturic responses. Furthermore, treatment with Salviae miltiorrhizae Radix significantly increased glomerular filtration rate, renal plasma flow, and renal blood flow.