3-METHOXYBENZYL (3-MPM) AND 3, 5-DIMETHOXYBENZYL (3, 5-DMPM) PROTECTING GROUPS FOR THE HYDROXY FUNCTION LESS READILY REMOVABLE THAN 4-METHOXYBENZYL (MPM) AND 3, 4-DIMETHOXYBENZYL (DMPM) PROTECTING GROUPS BY DDQ OXIDATION

Abstract

New protecting groups for the hydroxy function, 3-methoxybenzyl (3-MPM) and 3, 5-dimethoxybenzyl (3, 5-DMPM) groups are slowly removed by DDQ oxidation at room temperature and distinguished from readily removable 4-methoxybenzyl (MPM). They are stable to strong acids.