Studies on Quinolizine Derivatives. XXII. Syntheses and Properties of 2-Phenylazacycl [3.3.3] azine Derivatives

Abstract

By the reaction of 6-methyl-4-imino-4H-quinolizine derivatives (5, 8) with the mixed anhydrides (6a-h), 2-phenyl-1-azacycl [3.3.3] azines (7a-p, 9a-g) were obtained.2-Pheny1-1, 3, 6-triazacycl [3.3.3] azine derivatives (15ah, 17a-h, 18a-g) were prepared by the reaction of 2-(2-cyanovinyl) amino-6-aminopyridines (13, 16) with mixed anhydrides (6a-h).The proton nuclear magnetic resonance spectral data of the 2-phenylazacycl [3.3.3] azines (12, 18a) may be interprited in terms of a paramagnetic ring current.