Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
o2-cu2+-ASCORBIC ACID : A NOVEL OXIDATION SYSTEM FOR THE HIGHLY SELECTIVE O-CEALKYLATION OF 2-ALKOXYPHENOLS
Kazuhiro Aihara, Tsunehiko Higuchi, Masaaki Hirobe
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Keywords: catechol
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1988 Volume 36 Issue 2 Pages 837-840

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Abstract
The novel oxidation system "O2-Cu<2+>-ascorbic acid" is a selective reagent for the oxidative O-dealkyation of 2-alkoxyphenols and affords catechols in good yield.
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© The Pharmaceutical Society of Japan
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