YANDANZIOLIDE D, A NEW C₁9-QUASSINOID ISOLATED FROM BRUCEA JAVANICA (L.) MERR

Abstract

A new quassinoid, yadanziolide D, was isolated from Brucea javanica (L.) MERR and the structure was determined to be (5S, 10S)-13β, 20-epoxy-11β, 12α, 14, 15β-tetrahydroxy-16-oxo-1, 2-seco-1-nor-6(5→10)abeo-picras-3-en-2, 5-olide by the combined analysis of its various spectroscopic data and the X-ray analysis of its di-O-acetyl derivative using the Patterson fragment search.