1988 Volume 36 Issue 3 Pages 1233-1236
Synthetic Joro toxin (JSTX-3) was iodinated by the lactoperoxidase method and the reaction products were purified by high performance liquid chromatoqraphy. Proton-nuclear magnetic resonance spectroscopy revealed that iodination occurred mainly at position 3 of the benzene ring. The radio-iodinated JSTX-3 appeared autoradiographically to be accumulated in the synapse area of the lobster nerve-muscle preparation.