Saponins from Leaves of Acanthopanax senticosus HARMS., Ciwujia. II. : Structures of Ciwujianosides A₁, A₂, A₃, A₄ and D₃

Abstract

Further investigation of the chemical constituents of the leaves of Acanthopanax senticosus HARMS. resulted in the isolation of five new triterpenoid saponins, named ciwujianosides A₁ (1), A₂ (2), A₃ (3), D₃(4) and A₄ (5). The structures of these saponins were elucidated as follows : 1, 3-O-β-glucopyranosyl-(1→2)-α-arabinopyranosyloleanolic acid 28-O-α-rhamnopyranosyl-(1→4)-β-glucopyranosyl-(1→6)-β-glucopyranosyl ester; 2, 3-O-β-glucopyranosyl-(1→2)-α-arabinopyranosyl-30-norolean-12, 20(29)-dien-28-oic acid 28-O-α-rhamnopyranosyl-(1→4)-β-glucopyranosyl-(1→6)-β-glucopyranosyl ester; 3, 3-O-α-rhamnopyranosyl-(1→2)-α-arabinopyranosylmesembryanthemoidigenic acid 28-O-α-rhamnopyranosyl-(1→4)-β-glucopyranosyl-(1→6)-β-glucopyranosyl ester; 4, 3-O-α-arabinopyranosylmesembryanthemoidigenic acid 28-O-α-rhamnopyranosyl-(1→4)-6-O-acetyl-β-glucopyranosyl-(1→6)-β-glucopyranosyl ester; 5, 3-O-β-glucopyranosyl-(1→2)-α-arabinopyranosylmesembryanthemoidigenic acid 28-O-α-rhamnopyranosyl-(1→4)-6-O-acetyl-β-glucopyranosyl-(1→6)-β-glucopyanosyl ester.