Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Two New neo-Clerodane Diterpenes in Ajuga decumbens
Zhi-da MINMizuo MIZUNOShi-qiang WANGMunekazu IINUMAToshiyuki TANAKA
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1990 Volume 38 Issue 11 Pages 3167-3168

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Abstract

Study on the chemical constituents of Ajuga decumbens resulted in the isolation of two new minor neo-clerodane diterpenes, ajugacumbins E and F, together with a known diterpene, ajugamarin and an iridoid, 8-acetyl-harpagide.By means of spectroscopic analysis, structures of the new diterpenes were determined to be 1α, 3α, 6α-triacetoxy-4, 7-expoxy 18α-(2'-hydroxy-3'-methylene-butyryloxy)-neo-cleroda-13-en-15, 16-olide for ajugacumbin E, and 4α, 6α-dihyeroxy-4β-hrdroxymethyl-18α-tigloyloxy-neo-cleroda-13-en-15, 16-olide for ajugacumbin F.

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© The Pharmaceutical Society of Japan
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