Solute-Stationary Phase Interaction in Gas-Liquid Chromatography. : Evaluation of the Relative Retention Value for Substituted Halogenobenzene Derivatives

Abstract

Separation coefficients log γ for substituted halgenobenzene derivatives given by gas-liquid chromatography have been evaluated by regression analysis, using three kinds of descriptors, namely, σ_s°, μ²/α and Σσ^±_π. For the orthodisubstituted series, the descriptor Σσ^±_π, correcting the ortho effect due to the vicinal substituent group, is required. This correction can be achieved by evaluating the intensity drop of the p(¹La) band of ultraviolet absorption spectra. The Σσ^±_π of the regreession equation indicates the contribution of the charge-transfer interactionbetween the substrate and stationary liquid.