Studies on Aldose Reductase Inhibitors from Natural Products. IV. Constituents and Aldose Reductase Inhibitory Effect of Chrysanthemum morifolium, Bixa orellana and Ipomoea batatas

Satoshi TERASHIMA; Mineo SHIMIZU; Syunji HORIE; Naokata MORITA

doi:10.1248/cpb.39.3346

Satoshi TERASHIMA, Mineo SHIMIZU, Syunji HORIE, Naokata MORITA

Author information

Keywords: Chrysanthemum morifolium, Bixa orellana, Ipomoea batatas, aldose reductase inhibitor, ellagic acid, isoscutellarein, 3, 5-dicaffeoylquinic acid

JOURNAL FREE ACCESS

1991 Volume 39 Issue 12 Pages 3346-3347

DOI https://doi.org/10.1248/cpb.39.3346

Details

Abstract

The hot water extracts of Chrysanthemum morifolium, Bixa orellana and Ipomoea batatas, were found to have potent inhibitory activity towards lens aldose reductase (AR). Ellagic acid (4) was isolated from C. morifolium and I. batatas, isoscutellarein (7) from B. orellana and 3, 5-dicaffeoylquinic acid (10) from I. batatas, respectively, as potent inhibitors.

Corresponding author

Register with J-STAGE for free!