Incarnal. A New Antibacterial Sesquiterpene from Basidiomycetes

抄録

A new sesquiterpene, incarnal, was isolated from culture fluid of Gloeostereum incarnatum (Japanese name : Nikawaurokotake). Incarnal inhibited the growth of gram-positive bacteria at 6.25-12.5 μg/ml. The structure of incarnal has been determined to be (1-hydroxy-2, 10, 10-trimethyl)-3-methylene-tricyclo[6.3.0.0.^{2, 6}]undec-5, 7-diene-4, 9-dione by X-ray diffraction and spectroscopic methods.