Cycloleonurinin, a Cyclic Peptide from Leonuri Fructus

Kaoru KINOSHITA; Junko TANAKA; Keiko KURODA; Kiyotaka KOYAMA; Shinsaku NATORI; Takeshi KINOSHITA

doi:10.1248/cpb.39.712

Kaoru KINOSHITA, Junko TANAKA, Keiko KURODA, Kiyotaka KOYAMA, Shinsaku NATORI, Takeshi KINOSHITA

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Keywords: Leonuri Fructus, Leomurus artemisia, Leomurus sibiricus, cyclic peptide, FAB MS/MS, NMR

JOURNAL FREE ACCESS

1991 Volume 39 Issue 3 Pages 712-715

DOI https://doi.org/10.1248/cpb.39.712

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Abstract

From Leonuri Fructus, a cyclic peptide composed of twelve amino acid residues was isolated. The sequence of the residues was established by mass spectroscopy and by the use of a protein sequencer for the partial hydrolysates obtained by α-chymotrypsin.

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