Studies on the Nepalese Crude Drugs. XII. On the Phenolic Compounds from the Root of Scutellaria prostrata JACQ. ex BENTH.

Abstract

From the root of Scutellaria prostrata JACQ. ex BENTH., five compounds (I-V) were isolated, together with three known glycosides of phenylethanoid (IV-VIII) and sixteen known flavonoids (IX-XXIV). On the basis of chemical and spectral evidence, I-V were identified as 5, 6, 2', 6'-tetrahydroxy-7, 8-dimethoxyflavone, 5, 6, 2'-trihydroxy-7, 8, 6'-trimethoxyflavone, 5, 7, 2'-trihydroxy-8-methoxyflavone 7-O-β-D-glucuronopyranoside, 2-(3-hydroxy-4-methoxyphenyl)ethyl 1-O-β-D-glucopyranoside and 2-(3-hydroxy-4-methoxyphenyl)ethyl 1-O-β-D-(4-O-feruloyl)glucopyranoside, respectively. Compound II has already been synthesized.