Isolation of 10-O-Acyl Iridoid Glucosides from a Philippine Medicinal Plant, Oldenlandia corymbosa L. (Rubiaceae)

Abstract

From the aerial parts of Oldenlandia corymbosa, nine iridoid glucoside derivatives were isolated. On spectroscopic investigation, five known compounds were identified, that is, deacetyl asperuloside, asperuloside, asperulosidic acid, deacetyl asperulosidic acid and scandoside methyl ester. The structures of four new compounds were determined to be acylated derivatives of the known compounds, that is, 10-O-benzoyl deacetyl asperulosidic acid methyl ester, and 10-O-benzoyl, 10-O-p-hydroxybenzoyl, and 10-O-p-trans, cis-coumaroyl scandoside methyl esters.