HYBRIDIZATION OF OLIGODEOXYNUCLEOTIDE WITH REXOD COENZYME MODEL; SYNTHESIS AND PROPERTIES OF THYMIDINE DECAMERS COVALENTLY LINKED TO 5-DEAZAFLAVIN

Yoshiteru EIKYU; Yoshinori NAKAMURA; Taishin AKIYAMA; Fumio YONEDA; Kiyoshi TANAKA; Kaoru FUJI

doi:10.1248/cpb.40.291

Yoshiteru EIKYU, Yoshinori NAKAMURA, Taishin AKIYAMA, Fumio YONEDA, Kiyoshi TANAKA, Kaoru FUJI

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Keywords: DNA hydrid, 5-deazaflavin, antisense molecule, synthesis, fluorescence

JOURNAL FREE ACCESS

1992 Volume 40 Issue 1 Pages 291-293

DOI https://doi.org/10.1248/cpb.40.291

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Abstract

Modified thymidine decamers covalently linked to 5-deazaflavin derivatives through aminoalkyl spacer arm in the form of phosphoramidate bond, were prepared and characterized, Chemical and physical properties of the hydrid moleculeas are discussed.

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