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Chemical and Pharmaceutical Bulletin
Vol. 40 (1992) No. 5 P 1170-1176

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http://doi.org/10.1248/cpb.40.1170


A series of 75 imidazo[1, 2-α]pyrimidine derivatives were synthesized. The "in vitro" antibacterial activity of these compounds and their corresponding α-bromoketones against a variety of gram (+), gram (-) bacteria and Mycobacterium species is reported. Some of the prepared derivatives exhibited potent antimicrobial activity.

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