Indonesian Medicinal Plants. I. Chemical Structures of Calotroposides A and B, Two New Oxypregnane-Oligoglycosides from the Root of Calotropis gigantea (Asclepiadaceae)

Abstract

Two new oxypregnane-oligoglycosides named calotroposides A (1) and B (2) have been isolated from the root of Calotropis gigantea (Asclepiadaceae), an Indonesian medicinal plant, and their chemical structures have been elucidated by chemical and spectroscopic methods as 12-O-benzoyllineolon 3-O-β-D-cymaropyranosyl(1→4)-β-D-oleandropyranosyl(1→4)-β-D-oleandropyranosyl(1→4)-β-D-cymaropyranosyl(1→4)-β-D-cymaropyranoside and 12-O-benzoylde-acetylmetaplexigenin 3-O-β-D-cymaropyranosyl(1→4)-β-D-oleandropyranosyl(1→4)-β-D-oleandropyranosyl(1→4)-β-D-cymaropyranosyl(1→4)-β-D-cymaropyranoside, respectively.