FACILE ENZYMATIC PREPARATION OF ENANTIOMERIC β-LACTAMS

Hazuki NAGAI; Tatsushi SHIOZAWA; Kazuo ACHIWA; Yoshiyasu TERAO

doi:10.1248/cpb.40.2227

永井葉月, 塩沢竜志, 阿知波一雄, 寺尾良保

著者情報

キーワード: β-lactam, lipase, resolution, hydrolysis, esterification

ジャーナルフリー

1992 年 40 巻 8 号 p. 2227-2229

DOI https://doi.org/10.1248/cpb.40.2227

詳細

抄録

Optically active β-lactams were obtained conveniently by lipase-catalyzed enantioselective hydrolysis of 1-acyloxymethyl-2-azetidinones and esterification of 1-hydroxymethyl-3, 3-dimethyl-2-azetidinone with vinyl acetate in organic solvent.

責任著者(Corresponding author)

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