Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Chalcones as Synthetic Intermediates. A Facile Route to (±)-Magnosalicin, an Antiallergy Neolignan
Osamu MURAOKA, Tomoaki SAWADA, Eiichiro MORIMOTO, Genzoh TANABE
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Keywords: synthesis, magnosalicin, chalcone, neoligana, Magnolia salicifolia, organoselenium-induced cyclization
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1993 Volume 41 Issue 4 Pages 772-774

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Abstract
A facile synthetic route was developed to (±)-magnosalicin (1), a new type of neolignan with antiallergy activity isolated from Magnolia salicifolia, starting from a chalcone, 1, 3-bis(2', 4', 5'-trimethoxyphenyl)prop-2-en-1-one (3).
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© The Pharmaceutical Society of Japan
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