Synthesis of a Simple (±)-Dibenzocyclooctadiene Lignan, (±)-Normethylgomisin A

Abstract

(±)-Normethylgomisin A (3) was synthesized by the samarium-Barbier reaction of the phenylpropene 4 and the phenylacetone 5 to give the butanol 6, followed by oxidative aryl-aryl coupling reaction of the butanol.