CAMELLIASAPONINS B1, B2, C1 AND C2, NEW TYPE INHIBITORS OF ETHANOL ABSORPTION IN RATS FROM THE SEEDS OF CAMELLIA JAPONICA L.

Masayuki YOSHIKAWA; Emiko HARADA; Toshiyuki MURAKAMI; Hisashi MATSUDA; Johji YAMAHARA; Nobutoshi MURAKAMI

doi:10.1248/cpb.42.742

CAMELLIASAPONINS B₁, B₂, C₁ AND C₂, NEW TYPE INHIBITORS OF ETHANOL ABSORPTION IN RATS FROM THE SEEDS OF CAMELLIA JAPONICA L.

Masayuki YOSHIKAWA, Emiko HARADA, Toshiyuki MURAKAMI, Hisashi MATSUDA, Johji YAMAHARA, Nobutoshi MURAKAMI

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Keywords: Camellia japonica, Theaceae, ethanol absorption inhibitor, acylated oleanene-type triterpene monodesmoside, camelliasaponin B₁, camelliasaponin C₁

JOURNAL FREE ACCESS

1994 Volume 42 Issue 3 Pages 742-744

DOI https://doi.org/10.1248/cpb.42.742

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Abstract

New type inhibitors of ethanol absorption, camelliasaponins B₁, B₂, C₁ and C₂, were isolated from the seeds of Camellia japonica L. The structures of camelliasaponins were elucidated on the basis of chemical and physicochemical evidence. The inhibitory effect of camelliasaponins and related saponins on ethanol absorption have been examined, and it was found that the triterpene oligoglycoside structure having an acyl group was essential to exerting the activity.

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