Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
LIPASE-CATALYZED OPTICAL RESOLUTION OF 2-OXAZOLIDINONES
Hideaki WAKAMATSUYoshiyasu TERAO
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1996 Volume 44 Issue 1 Pages 261-263

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Abstract
Optically active 4- or 5-substituted 2-oxazolidinones were obtained by lipase-catalyzed enantioselective hydrolysis of the 3-acyloxymethyl-2-oxazolidinones and transesterification of the 3-hydroxymethyl-2-oxazolidinones with vinyl propionate in organic solvents.
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© The Pharmaceutical Society of Japan
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